Beilstein J. Org. Chem.2017,13, 1670–1692, doi:10.3762/bjoc.13.162
nitrogen heteroarenes.
Keywords: aerobic oxidation; bioinspiredFlavinmimics; nitrogen heteroarenes; organo catalytic; oxidative dehydrogenation; Introduction
By virtue of their presence in bioactive natural products and active pharmaceutical ingredients, nitrogen heterocycles and heteroaromatics form
electron-withdrawing substrates were favored in this case. A slight modification (5 mol % phd, 1 mol % ZnI2 and 1 mol % PPTS) of the existing procedure afforded indoles 62 from indolines 61.
Bioinspiredflavinmimics were also used as catalysts for oxidative dehydrogenation of dihydropyridines 63 and